What Is Orbital Proptosis?
Orbital proptosis refers to the abnormal protrusion of one or both eyes in relation to the orbits (bony compartments that normally house the eyes and surrounding structures). While most cases of orbital proptosis are due to Grave’s disease (resulting in Grave’s Ophthalmopathy), the condition can also be caused by growths within the orbit or adjacent sinuses, trauma, infection, and bleeding or abnormal blood flow within the orbit.
Grave’s Disease is an auto-immune condition, where antibodies that normally protect someone from outside pathogens instead attack and trigger inflammation within normal tissues within the body. In Grave’s Disease, these antibodies attack the thyroid gland and tissues within the orbit, leading to overgrowth of muscles and fat cells and displacement of the eye(s) forward to protrude from the orbits. As the eyelids may not provide adequate closure the more forward the eyes are displaced, this can lead to excessive dryness of the eyes and cause corneal irritation, abrasions, vision loss, as well as an undesired cosmetic appearance.2